Electrographic changes immediately recorded from the exposed human brain during cardiazol convulsion.

(Received for publication, September 15, 1949) Electro (encephalo) graphic studies of convulsion induced by cardiazol injection have hitherto given significant meanings in explanation of the cerebral mechanism for convulsion phenomenon and improvement of psychic cgndition.1)2)13)14) We also had once investigated electrographic changes during cardiazol convulsion in man.16) Those results, however, had bases upon the data obtained by means of the indirect recording method via the scalp. Now, those changes by the direct recording from the exposed human brain have come under investigation. Though such investiga tions have already been made by Forster and Altenburger,4) Meyers11) and, recently, Jasper,9) the changes correlated with the total course of convul sion which is experimentally, induced by cardiazol, are yet not reported. The purpose of this report is consisted from 1) an inquiring of the relation ship between the cortical pattern and the subcortical one and 2) a com parison of differences between electrographic hanges recorded via the scalp, viz. the routine EEG, and the changes of the cortical discharge. Some comments on the cerebral mechanism for convulsion are also added.